Back to article: Alzheimer’s disease: amyloid-based pathogenesis and potential therapies

FIGURE 3: Current treatment strategies based on the amyloid cascade hypothesis. Recent or ongoing clinical trials have mainly focused on inhibition of β-secretase (BACE-1), γ-secretase, or immunization strategies against Aβ monomers or plaques. See text for details. CTFβ, C-terminal fragment beta.

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