Back to article: Foie gras and liver regeneration: a fat dilemma

TABLE 1. Summary of effects of Non-alcoholic fatty liver disease (NAFLD) in various models on liver regeneration.

19. Yang SQ, Lin HZ, Mandal AK, Huang J, Diehl AM (2001). Disrupted signaling and inhibited regeneration in obese mice with fatty livers: implications for nonalcoholic fatty liver disease pathophysiology. Hepatology 34(4 Pt 1): 694-706.

21. DeAngelis RA, Markiewski MM, Taub R, Lambris JD (2005). A high-fat diet impairs liver regeneration in C57BL/6 mice through overexpression of the NF-kappaB inhibitor, IkappaBalpha. Hepatology 42(5): 1148-1157.

56. Picard C, Lambotte L, Starkel P, Sempoux C, Saliez A, Van den Berge V, Horsmans Y (2002). Steatosis is not sufficient to cause an impaired regenerative response after partial hepatectomy in rats. J Hepatol 36(5): 645-652.

57. Yamauchi H, Uetsuka K, Okada T, Nakayama H, Doi K (2003). Impaired liver regeneration after partial hepatectomy in db/db mice. Exp Toxicol Pathol 54(4): 281-286.

169. Uetsuka K, Shirai M, Yamauchi H, Nakayama H, Doi K (2005). Impaired proliferation of non-parenchymal cells participates in an impairment of liver regeneration in db/db mice. Exp Mol Pathol 79(1): 51-58.

170. Leclercq IA, Field J, Farrell GC (2003). Leptin-specific mechanisms for impaired liver regeneration in ob/ob mice after toxic injury. Gastroenterology 124(5): 1451-1464.

171. Leclercq IA, Vansteenberghe M, Lebrun VB, VanHul NK, Abarca-Quinones J, Sempoux CL, Picard C, Starkel P, Horsmans YL (2006). Defective hepatic regeneration after partial hepatectomy in leptin-deficient mice is not rescued by exogenous leptin. Lab Invest 86(11): 1161-1171.

172. Torbenson M, Yang SQ, Liu HZ, Huang J, Gage W, Diehl AM (2002). STAT-3 overexpression and p21 up-regulation accompany impaired regeneration of fatty livers. Am J Pathol 161(1): 155-161.

173. Tanoue S, Uto H, Kumamoto R, Arima S, Hashimoto S, Nasu Y, Takami Y, Moriuchi A, Sakiyama T, Oketani M, Ido A, Tsubouchi H (2011). Liver regeneration after partial hepatectomy in rat is more impaired in a steatotic liver induced by dietary fructose compared to dietary fat. Biochem Biophys Res Commun 407(1): 163-168.

174. Sydor S, Gu Y, Schlattjan M, Bechmann LP, Rauen U, Best J, Paul A, Baba HA, Sowa JP, Gerken G, Canbay A (2013). Sydor S, Gu Y, Schlattjan M, Bechmann LP, Rauen U, Best J, Paul A, Baba HA, Sowa JP, Gerken G, Canbay A. Lab Invest 93(1): 20-30.

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