Back to article: A game of substrates: replication fork remodeling and its roles in genome stability and chemo-resistance


FIGURE 2: Fork remodeling as interlocked cycles of reversal and resection. A framework to visualize remodeling of stalled forks as connected, dynamic states that are characterized by prevalence of reversal or restoration, and resection or protection. Gray rectangles mark exposure of parental ssDNA and purple rectangles – nascent ssDNA. Both can be used as markers of fork state.

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