FIGURE 2: Reversal of MSL-7-induced metabolic improvement in HDF-fed mice by an autophagy inhibitor. MSL-7 was administered to mice fed HFD for 8 weeks with or without DMKG, an inhibitor of autophagy. Nonfasting blood glucose level was monitored during administration of MSL-7 and DMKG to HFD-fed mice for 8 weeks (left). Intraperitoneal glucose tolerance test was conducted after 8 weeks of administration (right).