Back to article: Remodeling of mitochondrial morphology and function: an emerging hallmark of cellular reprogramming

FIGURE 4: Mitochondrial dynamics. Mitochondrial fusion and fission are regulated by guanosine triphosphatases (GTPases) proteins: DRP1 mediates fission, OPA1 and Mitofusins (not shown) regulate mitochondrial fusion. In stem cells, the anti-apoptotic protein MCL1 has been shown to interact with DRP1 at the outer mitochondrial membrane and with OPA1 at the matrix.

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