Back to article: The OFD1 protein is a novel player in selective autophagy: another tile to the cilia/autophagy puzzle

FIGURE 1: The centrosomal protein OFD1 controls autophagy. OFD1 promotes the selective autophagy-mediated degradation of ATG13, a component of ULK1 autophagy initiation complex. Loss of OFD1 determines ULK1 complex enhanced protein stability associated with excessive autophagy (Adapted from Morleo M et al. (2020), EMBO J, doi: 10.15252/embj.2020105120).

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