Back to article: GFI1’s role in DNA repair suggests implications for tumour cell response to treatment

FIGURE 1: Model for the action of GFI1 in DNA repair. GFI1 acts as a bridge between the PRMT1 methyltransferase and key DNA repair proteins to promote their activity. Methylation of MRE11 and the corresponding facilitation of HR repair are shown as an example of this activity of GFI1.

By continuing to use the site, you agree to the use of cookies. more information

The cookie settings on this website are set to "allow cookies" to give you the best browsing experience possible. If you continue to use this website without changing your cookie settings or you click "Accept" below then you are consenting to this. Please refer to our "privacy statement" and our "terms of use" for further information.