FIGURE 3: Schematic of differential LV remodelling post hemorrhagic MI with and without oral administration of deferiprone. Iron deposits from post-reperfusion intramyocardial hemorrhage drives the negative ventricular remodeling mechanistically towards fatty degeneration. However, intervention of deferiprone disrupts the iron-mediated degeneration and drives the heart towards positive remodeling. The area of MI is shown as black area on left ventricle in the top image, intramyocardial hemorrhage is shown as red area on image second from the top; negative left-ventricular remodeling is depicted by dilated left ventricle on DFP- image with semicircular white area representing lipomatous metaplasia; DFP+ image is shown with normal sized LV. Figure was generated using Biorender.

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