Table of contents

Volume 7, Issue 6, pp. 46 - 49, June 2023

Issue cover
Cover: This month in Cell Stress: Antibiotics and cancer. EM-image of methicillin-resistant Staphylococcus areus. Public domain image credit: National Institute of Allergy and Infectious Diseases (NIAID)/NIH. Edited by Cell Stress. The cover is published under the CC BY 4.0 license. Enlarge issue cover

News and Thoughts

Novel insights at the crossroads of antibiotic use and cancer risk

Nermina Malanovic and Djenana Vejzovic

page 46-49 | 10.15698/cst2023.06.280 | Full text | PDF | Abstract

The continuous use of antibiotics is associated with the spread of antimicrobial resistances and the not yet clear link to cancer development. Many conventional antibiotics have already shown different effects on a variety of cancer types raising questions for their rational use in cancer. However, discrepancy in the observed trend for some antibiotics reducing cancer development and being associated with higher risk of cancer underscores the lack of understanding the complex link between antibiotics and cancer. Here, we briefly summarize the possible antibiotic-mediated effects on cancer and conclude that those effects can be direct via i) specific targeting of tumor/cancer, ii) antimicrobial activity and iii) immunomodulatory activity whereby iv) indirectly caused effects primarily affect immune equilibrium between bacteria, cancer and immune cells. Furthermore, we also conclude that there is a great need for bulk profiling, comprehensive screening programs in all countries and in-depth studies to understand the risks and benefits of antibiotic use.

By continuing to use the site, you agree to the use of cookies. more information

The cookie settings on this website are set to "allow cookies" to give you the best browsing experience possible. If you continue to use this website without changing your cookie settings or you click "Accept" below then you are consenting to this. Please refer to our "privacy statement" and our "terms of use" for further information.