TABLE 1. Therapeutic strategies targeting mitochondria in cancer with clinical perspectives.

* withdrawn from clinical studies. DRP1 – dynamin-related protein 1; ETC – electron transport chain; GLUT – glucose transporter; GST- glutathione S-transferase; HK – hexokinase; IDH – isocitrate dehydrogenase; ROS – reactive oxygen species; TCA – tricarboxylic acid (cycle).